An ultra-expansible chitosan-silk fibroin miniaturized sponge loaded with tranexamic acid modified gelatin for coagulation abnormalities

Key Points

• Improved coagulation abnormalities are associated with loading tranexamic acid into the sponge.
• The miniaturized sponge demonstrated enhanced healing properties, supporting earlier intervention methodologies.
• Assessment of the modified gelatin within the sponge shows promising results for clotting effectiveness against various conditions.
• Potential applications for this biomaterial could benefit therapies related to diverse bleeding disorders.