Analysis of comorbid characteristics, molecular mechanisms between mild cognitive impairment and Alzheimer’s disease with interventions in a community-based population in Shanghai

Key Points

• Mild cognitive impairment patients are at high risk of Alzheimer's disease, highlighting urgent intervention needs.
• Intervention with boldine and piceatannol may offer potential benefits in cognitive function based on identified comorbidities.
• Observational analysis in a community-based population reveals the impact of lifestyle factors on cognitive impairment.
• Findings support early intervention strategies to prevent the progression from mild cognitive impairment to Alzheimer's.