Methylation-based forensic age estimation on different biogeographic backgrounds: A study on Central Europeans, East Asians and West Africans

Key Points

• Age estimation accuracy varies significantly among diverse biogeographic backgrounds, affecting forensic applications.
• Methylation profiles associated with age displayed variation when analyzed across Central Europeans, East Asians, and West Africans.
• Analysis focused on genetic markers and population stratification to assess age estimation methods.
• Findings highlight the need for localized forensic approaches to improve age estimation reliability.