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Liquid biopsy biomarkers for accurate detection of malignant pulmonary nodules: a meta-analytic approach | Synapse
March 3, 2026
Open Access
Liquid biopsy biomarkers for accurate detection of malignant pulmonary nodules: a meta-analytic approach
AC
Alberto Caballero-Vazquez
MG
Marta Garcia-Cerezo
LF
Laura R. Fernandez-Castro
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Key Points
Accurate detection of malignant pulmonary nodules is linked to various liquid biopsy biomarkers, enhancing diagnosis.
The meta-analysis showed a significant correlation with biomarkers, achieving sensitivity rates as high as 93% in some analyses.
Using meta-analysis across multiple studies allows a comprehensive assessment of liquid biopsy effectiveness in tumor identification.
Findings support the potential use of liquid biopsy biomarkers as a reliable, non-invasive alternative for diagnosing lung cancer.
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Caballero-Vazquez et al. (Thu,) studied this question.
synapsesocial.com/papers/69a75de2c6e9836116a2829f
https://doi.org/https://doi.org/10.1007/s12672-025-03646-1