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Can hair concentrations of artemether-lumefantrine be used as a tool to retrospectively determine drug exposure during malaria treatment? | Synapse
March 3, 2026
Open Access
Can hair concentrations of artemether-lumefantrine be used as a tool to retrospectively determine drug exposure during malaria treatment?
JS
Jenny L Schnyder
Netherlands Center for Occupational Diseases
MM
Marloes Vos-van der Meer
RH
Reinier M. van Hest
Amsterdam Neuroscience
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Key Points
Hair concentrations of artemether-lumefantrine may indicate drug exposure during malaria treatment, enhancing monitoring.
Key findings demonstrate a correlation between drug levels in hair and reported exposure, aiding retrospective assessments.
The method relies on measuring specific compounds in hair samples to infer previous drug intake effectively.
These observations highlight potential applications in evaluating treatment adherence and informing clinical practices.
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Schnyder et al. (Wed,) studied this question.
synapsesocial.com/papers/69a75de9c6e9836116a28364
https://doi.org/https://doi.org/10.5167/uzh-283252
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