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Social Determinants of Health, Genetic Susceptibility and Risk of Dementia: A Prospective Cohort Study | Synapse
March 3, 2026
Social Determinants of Health, Genetic Susceptibility and Risk of Dementia: A Prospective Cohort Study
HC
Huan Chen
Chengdu University of Traditional Chinese Medicine
XW
Xiao-Lin Wang
Southern Medical University
JG
Jian Gao
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Key Points
Dementia risk significantly correlates with genetic susceptibility and social determinants of health.
Findings indicate a 30% increased risk in individuals with specific genetic markers and adverse social conditions.
Prospective cohort study utilized comprehensive assessments of social factors and genetic backgrounds over a 5-year timeframe.
Implications highlight the urgent need for addressing social determinants alongside genetics to lower dementia incidence.
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Cite This Study
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Chen et al. (Thu,) studied this question.
synapsesocial.com/papers/69a75e0bc6e9836116a28667
https://doi.org/https://doi.org/10.1016/j.amepre.2026.108294