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Molecular features of human pathological tau distinguish tauopathy-associated dementias | Synapse
March 3, 2026
Open Access
Molecular features of human pathological tau distinguish tauopathy-associated dementias
MK
Mukesh Kumar
Boston Children's Hospital
CS
Christoph N. Schlaffner
Hasso Plattner Institute
ST
Shaojun Tang
Boston Children's Hospital
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Key Points
Pathological tau shows unique molecular features linked to dementia.
Key biomarkers identified in different types of tauopathy can distinguish symptoms.
Analysis of tau protein in human samples enhances understanding of neurodegenerative diseases.
Findings may enable more precise diagnosis of dementias related to tauopathy.
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Cite This Study
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Kumar et al. (Thu,) studied this question.
synapsesocial.com/papers/69a75e1ac6e9836116a2878f
https://doi.org/https://doi.org/10.1016/j.cell.2025.12.036