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Outcomes of valproic acid withdrawal in females before or during pregnancy: A systematic review and meta-analysis | Synapse
March 3, 2026
Outcomes of valproic acid withdrawal in females before or during pregnancy: A systematic review and meta-analysis
MB
M. Claudia Burbano
RC
R Grace Couper
PE
Poul Espino
Western University
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Key Points
Withdrawal from valproic acid may influence neurodevelopmental outcomes for infants.
The analysis included data from multiple studies, examining various withdrawal timelines.
Systematic review and meta-analysis methods were used to assess existing literature on this topic.
Findings highlight the need for careful consideration of valproic acid use before and during pregnancy.
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Burbano et al. (Thu,) studied this question.
synapsesocial.com/papers/69a75e2ec6e9836116a2894c
https://doi.org/https://doi.org/10.1016/j.seizure.2026.01.019
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