This study demonstrates the heterogenous and phage-dependent efficacy of available inactivation buffers, underscoring the critical necessity for researchers to empirically screen their specific phage isolates against chosen inactivation methods. This is crucial to ensure that observed antibacterial effects are correctly attributed to phage activity during the experimental period, rather than to uncontrolled phage carry-over, thereby enhancing the reliability and interpretability of results.
Torres et al. (Thu,) studied this question.