Spatially differential gold nanocluster amplification of LSPR for ultrasensitive, label-free optical immunoassays

Key Points

• Enhanced detection sensitivity achieved through local surface plasmon resonance (LSPR) amplification using gold nanoclusters.
• The system allows for label-free optical immunoassays, simplifying the detection process and reducing costs.
• Utilized current advances in nanotechnology to improve the performance of immunoassays for biomolecular interactions.
• Findings suggest that application could lead to significant improvements in diagnostic capabilities.