Chemoproteomics-based profiling elucidates the antimalarial effects of amodiaquine through disruption of glycolysis process in Plasmodium falciparum | Synapse
March 3, 2026Open Access
Chemoproteomics-based profiling elucidates the antimalarial effects of amodiaquine through disruption of glycolysis process in Plasmodium falciparum
Key Points
Amodiaquine effectively disrupts glycolysis, leading to significant antimalarial effects.
The study utilizes chemoproteomics to profile interactions impacting metabolic pathways in Plasmodium falciparum.
Findings indicate a strong connection between glycolysis inhibition and antimalarial efficacy of amodiaquine.
The disruption of glycolysis by amodiaquine offers insights into potential new treatment approaches for malaria.