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Survivin/BIRC5-derived peptide disrupts survivin dimerization and cell division and induces multifaceted anti-cancer effects | Synapse
March 3, 2026
Open Access
Survivin/BIRC5-derived peptide disrupts survivin dimerization and cell division and induces multifaceted anti-cancer effects
MS
Manikandan Santhanam
VB
Venkatadri Babu
AS
Anna Shteinfer-Kuzmine
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Key Points
The survivin-derived peptide disrupts survivin dimerization, leading to altered cell division.
Significant anti-cancer effects are observed through this peptide, impacting tumor growth.
Analysis utilized in vitro experimental approaches to assess the peptide's function on cancer cells.
Supports further investigations into survivin-targeting therapies for cancer treatment.
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Santhanam et al. (Fri,) studied this question.
synapsesocial.com/papers/69a75e98c6e9836116a29594
https://doi.org/https://doi.org/10.1016/j.omton.2026.201142