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Ravulizumab for acute exacerbations in neuromyelitis optica spectrum disorder: A report of three cases | Synapse
March 3, 2026
Ravulizumab for acute exacerbations in neuromyelitis optica spectrum disorder: A report of three cases
MM
Masahiro Mori
Chiba University
AU
Akiyuki Uzawa
TM
Takahiro Makino
Chibaken Saiseikai Narashino Hospital
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Key Points
Ravulizumab effectively reduces acute exacerbations in neuromyelitis optica spectrum disorder, improving symptoms.
In three cases, patients showed significant recovery following ravulizumab treatment, with improved clinical measures.
Observational assessment of three cases illustrated clinical decisions on immunotherapy approaches for treatment options.
Highlights the need for further studies to confirm findings in larger, diverse patient populations.
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Mori et al. (Mon,) studied this question.
synapsesocial.com/papers/69a75ee8c6e9836116a29ee0
https://doi.org/https://doi.org/10.1016/j.jns.2025.124552