Targeting senescent cells in aged adipose tissue induced by ovarian cancer with the NF-κB inhibitor quercetin and resveratrol impedes the growth and metastasis of ovarian cancer
Key Points
Quercetin and resveratrol effectively reduce ovarian cancer growth and metastasis, improving treatment outcomes.
Experiments demonstrated a marked decrease in cancer cell spread in aged adipose tissue when NF-κB was inhibited.
Intervention involved targeting senescent cells in ovarian cancer models, focusing on the role of aging in tumor development.
Findings may help formulate new strategies for cancer therapy, particularly in older populations.