CFTR modulators partially restore the epithelial interferome in Aspergillus infection to improve clinical outcome

Key Points

• Improved clinical outcomes correlate with the restored epithelial interferome, enhancing responses to aspergillus infection.
• The study observed significant modulation of epithelial pathways in response to CFTR interventions and Aspergillus exposure.
• Assessment involved analyzing the impact of specific CFTR modulators on epithelial cells during infection with Aspergillus.
• Findings suggest potential for CFTR modulators as therapeutic options, warranting further exploration in clinical contexts.