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Przewaquinone A regulates cell cycle and autophagy through the SrC/STAT3 signaling pathway to inhibit colorectal cancer progression | Synapse
March 3, 2026
Przewaquinone A regulates cell cycle and autophagy through the SrC/STAT3 signaling pathway to inhibit colorectal cancer progression
JS
Jinsong Su
First Affiliated Hospital of Zhengzhou University
TW
Tianqi Wan
ST
Shengnan Tian
Key Points
Inhibition of colorectal cancer progression is achieved through modulation of cell cycle and autophagy.
This study identifies a significant role for the Src/STAT3 signaling pathway in cancer regulation.
Analyses demonstrate that Przewaquinone A effectively alters both cellular processes—cell cycle and autophagy.
Findings suggest potential therapeutic interventions targeting these pathways for colorectal cancer management.
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Su et al. (Sat,) studied this question.
synapsesocial.com/papers/69a75f3ec6e9836116a2a7a0
https://doi.org/https://doi.org/10.1007/s00210-026-05042-0