Nectamazin A from Piper crocatum as a bioactive compound against oral and throat diseases: In vitro and in silico study

Key Points

• Nectamazin A shows significant anti-bacterial activity against oral pathogens, suggesting its therapeutic potential.
• In vitro experiments reveal a 75% reduction in bacterial growth with nectamazin A compared to controls.
• Observational analysis of molecular interactions using in silico methods confirms the binding affinity of nectamazin A to key bacterial enzymes.
• These findings highlight the potential of bioactive compounds for developing new treatments against oral and throat diseases.