A sonographic median nerve enlargement in pregnant females with carpal tunnel: A systematic review and meta-analysis

Key Points

• Median nerve enlargement was consistently observed in pregnant females with carpal tunnel syndrome, linking the condition to pregnancy-related physiological changes.
• A notable increase in median nerve size was found in studies, with sonography measurements indicating a mean enlargement of 1.5mm over controls.
• Systematic review and meta-analysis included data from multiple studies, providing a comprehensive analysis of median nerve alterations in this population.
• Findings support the need for awareness and potential interventions during pregnancy to manage carpal tunnel symptoms effectively.