Sheep milk protects while cow milk exacerbates DSS-induced colitis by differentially modulating the Akkermansia–short chain fatty acids–barrier axis

Key Points

• Sheep milk appears to protect the gut barrier during DSS-induced colitis, enhancing recovery.
• Cow milk exacerbates inflammation in the gut, negatively affecting short chain fatty acids production.
• Analysis of DSS-induced colitis in a murine model highlights significant differences in milk type's effects.
• Further work is needed to explore the mechanisms behind the protective effects of sheep milk.