Integrating CT volume and plasma p-Tau217 for amyloid risk stratification in early stage Alzheimer's disease

Key Points

• Improved risk stratification for amyloid presence is linked to the integration of CT volume and plasma p-tau217 levels.
• A significant correlation was observed, with 72% of early-stage Alzheimer's cases effectively identified through this approach.
• Assessment involved cross-sectional data of patients at early Alzheimer stages, with a focus on biomarkers and imaging results.
• Integration may enhance diagnostic accuracy, yet external validation is needed to confirm effectiveness in diverse populations.