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Identification of an engram ensemble mediating memory forgetting in the dentate gyrus | Synapse
March 3, 2026
Identification of an engram ensemble mediating memory forgetting in the dentate gyrus
SH
Shiqiang Hu
JY
Jianfan Yang
SY
Siqi Yin
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Key Points
Memory forgetting is linked to specific engram ensembles in the dentate gyrus, playing a crucial role in human cognition.
The study finds that alterations in neural pathways can influence memory retrieval and forgetting processes over time.
This analysis investigates the correlation between engram ensembles and memory dynamics within the dentate gyrus.
These findings may suggest new approaches for enhancing cognitive functions and addressing memory-related disorders.
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Hu et al. (Sun,) studied this question.
synapsesocial.com/papers/69a7600ec6e9836116a2c78d
https://doi.org/https://doi.org/10.1016/j.neuron.2025.12.031