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March 3, 2026
Characterizing Differences in CAR-T cell Therapy Outcomes Based on Sex in Patients with Large B-cell Lymphoma
JB
John Behman
MA
Muhammad Bilal Abid
Key Points
CAR-T cell therapy outcomes differ significantly by sex, with variations noted in treatment responses.
Female patients demonstrated higher treatment efficacy, with a response rate observed at 75%.
Analysis of clinical records from lymphoma patients focused on assessing treatment outcomes by sex.
Understanding these differences may lead to personalized therapy strategies for better patient outcomes.
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Behman et al. (Sun,) studied this question.
synapsesocial.com/papers/69a76026c6e9836116a2c9c5
https://doi.org/https://doi.org/10.1016/j.jtct.2025.12.540
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Characterizing Differences in CAR-T cell Therapy Outcomes Based on Sex in Patients with Large B-cell Lymphoma | Synapse