Leukodystrophy-like phenotype in early-onset neuropsychiatric systemic lupus erythematosus: Case series and systematic review of the literature | Synapse
March 3, 2026
Leukodystrophy-like phenotype in early-onset neuropsychiatric systemic lupus erythematosus: Case series and systematic review of the literature
Key Points
The case series highlights a leukodystrophy-like phenotype associated with neuropsychiatric systemic lupus erythematosus.
Symptoms developed in early childhood, with progressive neuropsychiatric features noted.
Systematic review of literature complemented individual cases, revealing various presentations of the condition.
Recognition of this phenotype is crucial for timely diagnosis and management of systemic lupus erythematosus.