The role of VxrB in Vibrio harveyi and evaluation of a VxrB knock-out as a vaccine candidate

Key Points

• Knock-out of VxrB significantly diminishes pathogenicity in Vibrio harveyi, providing a promising vaccine candidate.
• Data from experiments indicate reduced virulence following VxrB knock-out, with a clear effect on infection rates.
• Observational analysis focusing on VxrB's role within the pathogenic mechanisms of Vibrio harveyi highlights its importance.
• This work may enable future vaccine developments against Vibrio species, targeting specific virulence factors like VxrB.