Disentangling violence in schizophrenia: Interactions between symptom trajectories, conduct disorder, and pharmacotherapy

Key Points

• Violent behavior is associated with specific symptom trajectories in schizophrenia, indicating a complex interaction.
• Participants exhibiting conduct disorder showed a higher risk of violence, highlighting overlapping risk factors.
• Analysis of treatment outcomes suggests that pharmacotherapy may mitigate violence linked to symptom severity.
• Findings may enable more targeted interventions for violence prevention in individuals with schizophrenia.