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Rho-associated kinase 1 (ROCK1) exerts distinct roles during the early infection versus replication phases of Minute Virus of Canines (MVC) | Synapse
March 3, 2026
Rho-associated kinase 1 (ROCK1) exerts distinct roles during the early infection versus replication phases of Minute Virus of Canines (MVC)
XR
Xiang Ren
SS
Shengbin Si
Ningxia Medical University
YX
Yishu Xiao
See all
Key Points
ROCK1 distinctly influences early infection and later replication phases of MVC, highlighting its potential as a therapeutic target.
The key finding indicates that ROCK1 modulates viral behavior at two different stages, underscoring its functional versatility.
Assessment of MVC infection phases explores the role of ROCK1, examining its distinct impacts on the virus throughout its lifecycle.
Understanding these phases could lead to novel treatments, as targeting ROCK1 may alter MVC's pathogenicity and improve outcomes.
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Ren et al. (Tue,) studied this question.
synapsesocial.com/papers/69a76060c6e9836116a2d123
https://doi.org/https://doi.org/10.1016/j.micpath.2026.108347