홈
탐색
nav.journalClub
트렌드
더보기
synapse
⌘+K
언어
한국어
March 3, 2026
A Neurotoxicity Mimic: Progressive Multifocal Leukoencephalopathy Following BCMA-Directed CART and Bispecific Therapies
MH
Muhammad Haidous
ZE
Zain El‐amir
University of Michigan
DF
David Frame
University of Michigan
See all
Key Points
Multifocal leukoencephalopathy occurs as a neurotoxic effect, impacting patient outcomes significantly.
Key evidence includes a notable increase in neurological symptoms in patients undergoing BCMA-directed CART.
Assessment using clinical data revealed the association between BCMA-directed CART and neurotoxicity manifestations.
The findings highlight the urgent need for careful monitoring during and after BCMA-directed CART treatments.
Mark Helpful
Like
Save
Bookmark
Relay
Share
Mark Helpful
Like
Save
Bookmark
Relay
Share
Cite This Study
Copy
Haidous et al. (Sun,) studied this question.
synapsesocial.com/papers/69a76063c6e9836116a2d15d
https://doi.org/https://doi.org/10.1016/j.jtct.2025.12.830
A Neurotoxicity Mimic: Progressive Multifocal Leukoencephalopathy Following BCMA-Directed CART and Bispecific Therapies | Synapse