High Incidence of Gvhd after Tapering Off Immunosuppression to Increase Donor T cell Chimerism

Key Points

• High incidence of graft-versus-host disease (Gvhd) follows tapering immunosuppression, posing risks.
• Observational analysis shows that increased donor T cell chimerism correlates with Gvhd incidence.
• This analysis evaluated immune responses in patients undergoing reduced immunosuppression protocols.
• Highlighting the need for careful monitoring during immunosuppression tapering to prevent Gvhd.