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Leveraging Human Derived Placental Matrix As a Media Additive to Enhance Expansion of Human Cord Blood CD34+ Cells | Synapse
March 3, 2026
Leveraging Human Derived Placental Matrix As a Media Additive to Enhance Expansion of Human Cord Blood CD34+ Cells
HB
Heather A Blackwell
CM
Calum McFetridge
CC
Cody W Carter
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Key Points
Cell expansion improved significantly with the use of placental matrix as a media additive.
Enhancement was notable with cord blood-derived CD34+ cells, leading to higher yields during culturing.
Assessment involved comparing growth rates of CD34+ cells with and without the placental matrix.
This finding suggests potential enhancements for cell therapy applications using placental-derived products.
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Blackwell et al. (Sun,) studied this question.
synapsesocial.com/papers/69a760a5c6e9836116a2d984
https://doi.org/https://doi.org/10.1016/j.jtct.2025.12.982