Revisiting the Obesity Paradox in Metabolic Dysfunction-associated Steatotic Liver Disease: Longitudinal Trajectory Analysis Reveals Time-varying Mortality Risks

Key Points

• Time-varying mortality risks are associated with metabolic dysfunction in individuals with obesity.
• This observation highlights significant variations in health outcomes over time, particularly in steatotic liver disease.
• Analysis included longitudinal data assessing changes in mortality risk related to obesity and metabolic dysfunction.
• Results may suggest a need for personalized health strategies for those with metabolic dysfunction.