miR-30e-5p in renal fibrosis: Cross-species multi-model profiling of dynamic networks and clinical prospects

Key Points

• Renal fibrosis is significantly influenced by microRNA signaling pathways, particularly miR-30e-5p.
• Key findings show that miR-30e-5p levels correlate with renal fibrosis severity in multiple species.
• Cross-species profiling was employed to assess dynamic networks of gene expression in renal tissues.
• Implications highlight the potential role of miR-30e-5p as a biomarker for monitoring renal fibrosis progression.