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Nobiletin alleviates alcoholic fatty liver disease by regulating lipid metabolism and oxidative stress via Ephx1 and Sult1a1 | Synapse
March 3, 2026
Nobiletin alleviates alcoholic fatty liver disease by regulating lipid metabolism and oxidative stress via Ephx1 and Sult1a1
HZ
Huilin Zhu
LZ
Lalai Zikela
DW
Dingli Wang
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Key Points
Nobiletin alleviates alcoholic fatty liver disease, positively impacting lipid metabolism and oxidative stress.
Results show significant regulation of ephx1 and sult1a1 pathways, highlighting their role in treatment efficacy.
Assessment of lipid profiles and oxidative markers was conducted through biochemical analysis and animal models.
Findings support potential therapeutic applications for nobiletin in managing alcoholic fatty liver disease.
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Zhu et al. (Sat,) studied this question.
synapsesocial.com/papers/69a76149c6e9836116a2f112
https://doi.org/https://doi.org/10.1016/j.phymed.2026.157977