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Correction: LRRK2 G2019S mutation contributes to mitochondrial transfer dysfunction in a Drp1-STX17-dependent manner | Synapse
March 3, 2026
Open Access
Correction: LRRK2 G2019S mutation contributes to mitochondrial transfer dysfunction in a Drp1-STX17-dependent manner
MD
Mei Ding
Nantong University
FW
Fen Wang
Nanjing University of Chinese Medicine
LJ
Lan‑Lan Jiang
Soochow University
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Key Points
Mitochondrial transfer dysfunction has been linked to the LRRK2 G2019S mutation, suggesting critical pathways.
Evidence shows that this mutation disrupts transfer functions through the Drp1-STX17 pathway.
Assessment of cellular processes demonstrates how the G2019S mutation affects mitochondrial dynamics.
These findings call for further exploration of targeted interventions in neurodegenerative diseases.
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Cite This Study
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Ding et al. (Sat,) studied this question.
synapsesocial.com/papers/69a7615fc6e9836116a2f3a0
https://doi.org/https://doi.org/10.1186/s40035-025-00533-1