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Hypocomplementemia With Cutaneous Vasculitis and Arthritis | Synapse
March 3, 2026
Hypocomplementemia With Cutaneous Vasculitis and Arthritis
FM
Frederic C. McDuffie
Centers for Disease Control and Prevention
WS
W. Mitchell Sams
JM
Jorge E. Maldonado
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Key Points
Hypocomplementemia was significantly associated with increased severity in cutaneous vasculitis and arthritis.
The analysis showed that 75% of patients exhibited both skin and joint symptoms, highlighting immune response alterations.
Observational case analysis of patients with autoimmune symptoms indicates a potential link with vascular inflammation.
Findings suggest a need for further studies on hypocomplementemia as a biomarker for autoimmune diseases.
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McDuffie et al. (Tue,) studied this question.
synapsesocial.com/papers/69a761c1c6e9836116a2fd12
https://doi.org/https://doi.org/10.1016/s0025-6196(26)07972-3
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