Multidimensional integrative analysis unveils genetic architecture, risk factors, and health consequences of brain aging

Key Points

• Comprehensive integration of neuroimaging and genomics helps uncover the underlying mechanisms of brain aging.
• The framework developed provides insight into risk factors that are critical for understanding brain health.
• Assessment using questionnaires and medical records enhances the multidimensional analysis of brain aging.
• These findings may enable targeted strategies for prevention, highlighting the need for personalized health approaches.