Ferroptosis-centered strategies: redefining therapeutic resistance & adaptation in modern oncology

Key Points

• Ferroptosis plays a crucial role in therapeutic resistance among cancer cells, offering new avenues for treatment.
• Analysis emphasizes the importance of signal transduction pathways in mediating resistance, and suggests potential new therapies.
• This review discusses ferroptosis-centered strategies that could redefine current approaches to cancer treatment and resistance.
• Identifying ferroptosis mechanisms could enable the development of more effective therapies, improving patient outcomes.