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March 3, 2026
Cepharanthine, a valuable sanative alternative for hepatocellular carcinoma through regulating Hippo-Yes-associated protein signal transduction
KH
Kejun Hu
YZ
Yukai Zhao
XF
Xinyu Fu
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Key Points
Cepharanthine demonstrates significant anti-cancer effects on hepatocellular carcinoma cells, altering signaling pathways.
The key evidence includes a marked reduction in tumor cell proliferation and increased apoptosis rates with treatment.
Exploration of the hippo pathway revealed cepharanthine's influence on yes-associated protein signaling in cancer cells.
This highlights the potential of cepharanthine as a new treatment option for liver cancer, suggesting further clinical studies are needed.
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Hu et al. (Tue,) studied this question.
synapsesocial.com/papers/69a765c4badf0bb9e87da5e9
https://doi.org/https://doi.org/10.1016/j.molpha.2026.100105
Cepharanthine, a valuable sanative alternative for hepatocellular carcinoma through regulating Hippo-Yes-associated protein signal transduction | Synapse