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March 3, 2026
Three-component synthesis of β-acyloxyl alkenyl amides for carboxylic acid/amino acid activation toward peptide and carboxylic acid derivatives synthesis
DJ
Dong-Fang Jiang
FZ
Fei Zeng
State Ethnic Affairs Commission
RY
Rongnan Yi
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Key Points
The synthesis method effectively activates carboxylic acids and amino acids, enhancing peptide synthesis.
Using β-acyloxyl alkenyl amides, the research showcases a three-component reaction for effective derivatives synthesis.
The approach reveals significant potential for creating a range of carboxylic acid derivatives and peptides efficiently.
This innovative method may inspire new strategies in organic synthesis, broadening the scope of chemical research.
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Jiang et al. (Sun,) studied this question.
synapsesocial.com/papers/69a765d4badf0bb9e87daa15
https://doi.org/https://doi.org/10.1016/j.cclet.2026.112488
β-아실옥시 알켄일 아미드의 3성분 합성: 펩타이드 및 카복실산 유도체 합성을 위한 카복실산/아미노산 활성화 | Synapse