March 3, 2026Open Access

Short-term vs. overnight insemination: which one is better for patients with only one or two oocytes retrieved in IVF cycles?

Key Points

Short-term insemination shows no negative impacts on clinical live birth rates (CLBR) despite low oocyte yields.
Potential benefits are noted for patients extending embryo culture to the blastocyst stage.
Assessment involves IVF cycles with only one or two oocytes for insemination timing effects.
Findings suggest reconsideration of insemination strategies may yield better outcomes for targeted patients.

Abstract

Our analysis suggests that for IVF cycles with a limited oocyte yield (1-2), short-term insemination does not adversely affect the CLBR. Furthermore, it may demonstrate a potential benefit for the subset of patients whose clinical pathway involves the extended culture of all embryos to the blastocyst stage.

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Cite This Study

Chen et al. (Tue,) studied this question.

synapsesocial.com/papers/69a76681badf0bb9e87dd3fd https://doi.org/https://doi.org/10.3389/fendo.2026.1647862

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