Polysaccharide-based inflammatory microenvironment-responsive nanocarriers for ulcerative colitis: Advances in design, mechanisms, and therapeutic applications

Key Points

• Therapeutic applications of polysaccharide-based nanocarriers target the inflammatory microenvironment in ulcerative colitis, providing new treatment options.
• Nanocarriers demonstrate enhanced drug delivery effectiveness, especially under inflammatory conditions, ultimately improving patient outcomes.
• Assessment of design and mechanisms highlights the importance of polysaccharide interactions with inflammatory cells in the gastrointestinal tract.
• Findings suggest that developing responsive nanocarriers could significantly enhance therapy effectiveness for ulcerative colitis patients.