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March 3, 2026
Open Access
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Reliable detection of Host-Microbe Signatures in cancer using PRISM
BG
Bassel Ghaddar
Rutgers, The State University of New Jersey
EC
Eugene B. Chang
Northwestern University
SD
Subhajyoti De
Key Points
Detection of host-microbe signatures in cancer is reliable and potentially transformative.
The method demonstrates high accuracy with a validation metric above 90%.
Analysis of diverse cancer samples using PRISM ensures a robust evaluation of microbial interactions.
The findings call for further investigation of microbiome roles in cancer progression.
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Ghaddar et al. (Sun,) studied this question.
synapsesocial.com/papers/69a76794badf0bb9e87e179a
https://doi.org/https://doi.org/10.1016/j.ccell.2026.01.007
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Reliable detection of Host-Microbe Signatures in cancer using PRISM | Synapse