March 3, 2026Open Access

ECM remodeling-associated immune signatures and hub proteins: predictive markers and therapeutic targets for metastatic gastric cancer

Key Points

This study identifies key immune signatures related to ECM remodeling in metastatic gastric cancer microenvironments.
Notably, specific hub proteins were highlighted as potential therapeutic targets, offering insights for cancer treatment.
Analysis demonstrates the intricate role of ECM remodeling, which may influence cancer progression and metastasis.
These findings may enable the development of innovative treatment strategies aimed at overcoming gastric cancer metastasis.

Abstract

This study not only reveals the complexity of ECM remodeling in the microenvironment of gastric cancer but also provides new perspectives and potential targets for future gastric cancer treatment and brings opportunities for the development of new therapeutics, which are expected to overcome the challenge of cancer metastasis.

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Cite This Study

Hu et al. (Fri,) studied this question.

synapsesocial.com/papers/69a76799badf0bb9e87e1957 https://doi.org/https://doi.org/10.3389/fimmu.2026.1765095

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