The role of neural derived extracellular vesicles micro-ribonucleic acid cargo in white matter integrity in early-onset and late-onset bipolar disorder

Key Points

• Extracellular vesicles' micro-RNAs are linked to white matter integrity in bipolar disorder.
• Key evidence suggests differing impacts in early-onset versus late-onset bipolar disorder.
• Analysis focused on genetic and molecular pathways influencing neuronal signaling and white matter function.
• Understanding these mechanisms highlights potential therapeutic targets for bipolar disorder.