Combination of sodium pentaborate pentahydrate, curcumin and piperine treatment induces ferroptosis in hepatocellular carcinoma cells by regulating iron homeostasis and ROS activity in vitro | Synapse
March 3, 2026
Combination of sodium pentaborate pentahydrate, curcumin and piperine treatment induces ferroptosis in hepatocellular carcinoma cells by regulating iron homeostasis and ROS activity in vitro
Key Points
Ferroptosis is effectively induced in hepatocellular carcinoma cells through the treatment.
Key findings reveal significant modulation of iron homeostasis and reactive oxygen species activity.
Combination therapy includes sodium pentaborate pentahydrate, curcumin, and piperine, enhancing efficacy.
Potential clinical implications include targeting cancer metabolism through ferroptosis induction.