March 3, 2026European Respiratory Journal1 citations

Inflammation and mucus properties in inherited diseases of mucociliary clearance

Key Points

Inflammation significantly affects mucus properties in inherited diseases.
Primary ciliary dyskinesia (PCD) and cystic fibrosis (CF) lead to bronchiectasis due to mucociliary dysfunction.
Assessment reveals critical roles of inflammation and mucus in respiratory conditions.
Findings suggest potential therapeutic targets for managing chronic respiratory symptoms.

Abstract

Extract Primary ciliary dyskinesia (PCD) and cystic fibrosis (CF) are inherited disorders of mucociliary clearance that lead to persistent lifelong productive cough, frequent exacerbations and, ultimately, bronchiectasis 1, 2.

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