Bidirectional Mendelian randomization of leukocyte counts, renal function, and Lipocalin-2 Levels: disentangling the genetic links, causal pathways and cardiovascular outcomes

Key Points

• Causal pathways involving lipocalin-2 are highlighted, suggesting significant health implications.
• The study examines genetic influences on leukocyte counts and renal function.
• Using Mendelian randomization, it assesses cardiovascular risks associated with these biomarkers.
• Findings underscore the need for further exploration of these genetic links to improve health strategies.