Chitosan-mediated enhanced hypericin biosynthesis in St. John’s wort (Hypericum perforatum) hairy root cultures

Key Points

• Hypericin biosynthesis is enhanced with chitosan treatment—demonstrating potential for increased production.
• Cultures showed a significant increase in hypericin levels by 40% following chitosan application.
• Assessment using hairy root cultures derived from St. John's wort indicates strong biosynthetic activity.
• This approach highlights the possibility of utilizing chitosan to increase phytochemical yields in plant cultures.