Clonal haematopoiesis and risk of incident rheumatoid arthritis: results from the UK biobank

Key Points

• The aim is to evaluate the relationship between common CHIP mutations and the risk of developing rheumatoid arthritis.
• Utilized data from the UK Biobank with extensive outpatient and hospital record follow-up.
• Focused on individuals with complete health records.
• Analyzed specific mutations in relation to rheumatoid arthritis incidence.
• No associations were found between TET2, TP53, and SF3B1 mutations and the risk of incident rheumatoid arthritis.
• Results were consistent even among those with the most complete health data.