Condom-protected penile-vaginal sex was associated with minimal genital microbiome changes, whereas condomless penile-vaginal sex among established couples led to extensive exchange of genital microbiota. Most disruptions to the microbiome resolved within 2-3 days, although changes in vaginal pH were associated with longer-lasting increases in Gardnerella abundance. Video Abstract.
Park et al. (Thu,) studied this question.