Preparation of covalent organic frameworks coated with cell membrane for precise analysis of cancer exosomes

Key Points

• The research aims to develop a selective biosensor for the detection of cancer-related exosomes using covalent organic frameworks.
• Developed a biosensor integrating cell membrane-coated covalent organic frameworks.
• Conducted electrochemical analysis for detecting homologous exosomes.
• Utilized cell membrane properties for enhanced biodetection.
• Achieved selective detection of homologous exosomes.
• Demonstrated improved sensitivity in exosome analysis compared to traditional methods.